Corbus Pharmaceuticals Holdings, Inc.CRBP
What Corbus Pharmaceuticals Holdings, Inc. does.
All references in this report to “Corbus,” the “Company,” “we,” “us,” or “our” mean Corbus Pharmaceuticals Holdings, Inc. and its subsidiaries unless we state otherwise, or the context otherwise indicates.
Corbus Pharmaceuticals Holdings, Inc. (the “Company” or “Corbus”) is a clinical stage company focused on promising new therapies in oncology and obesity and is committed to helping people defeat serious illness by bringing innovative scientific approaches to well-understood biological pathways. Corbus’ pipeline includes CRB-701, a next-generation antibody drug conjugate ("ADC") that targets the expression of Nectin-4 on cancer cells to release a cytotoxic payload of monomethyl auristatin E ("MMAE") and CRB-913, a highly peripherally restricted cannabinoid type-1 ("CB1") receptor inverse agonist for the treatment of obesity.
CRB-701 (SYS6002) is a novel clinical stage ADC that targets the expression of Nectin-4 on cancer cells to release a cytotoxic payload of MMAE. In February 2023, the Company obtained a license from CSPC Megalith Biopharmaceutical Co. Ltd. (“CSPC”), a subsidiary of CSPC Pharmaceutical Group Limited, to develop and commercialize the drug in the United States (“U.S.”), Canada, the European Union (including the European Free Trade Area), the United Kingdom (“U.K.”) and Australia. The Company is conducting a Phase 1/2 study in the U.S. and Europe (the "Western study") enrolling patients with advanced solid tumors associated with Nectin-4 expression. The dose expansion phase of the clinical trial is ongoing. In June 2025, the Company began dosing participants in the PD-1 combination arm with CRB-701 in combination with Keytruda® (pembrolizumab). The Company has received fast track designation for CRB-701 from the U.S. Food and Drug Administration (the "FDA") for the treatment of relapsed or refractory metastatic cervical cancer in December 2024 and in recurrent or metastatic head and neck squamous cell carcinoma (“HNSCC”) previously treated with platinum-based chemotherapy and an anti-PD(L)-1 therapy in September 2025. CRB-701 is currently being investigated by CSPC in a Phase 3 clinical trial in patients with cervical cancer in China (the "China study").
Revenue and profit, by fiscal year.
| Fiscal year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|
| Revenue | $3.9M | $881,705 | $0 | — | — | — |
| Net income | -$111.3M | -$45.6M | -$42.3M | -$44.6M | -$40.2M | -$78.5M |
| Free cash flow | -$100.2M | -$48.2M | -$37.6M | -$36.1M | -$41.8M | -$64.5M |
More on CRBP.
- Corbus Pharmaceuticals Holdings, Inc. summary
- Corbus Pharmaceuticals Holdings, Inc. financial statements
- Corbus Pharmaceuticals Holdings, Inc. key metrics
- Corbus Pharmaceuticals Holdings, Inc. health scores and style box
- Corbus Pharmaceuticals Holdings, Inc. earnings
- Corbus Pharmaceuticals Holdings, Inc. dividends
- Corbus Pharmaceuticals Holdings, Inc. valuation
- Corbus Pharmaceuticals Holdings, Inc. ownership and insiders
- Corbus Pharmaceuticals Holdings, Inc. peers
Figures from Corbus Pharmaceuticals Holdings, Inc.'s filings with the U.S. SEC, standardised automatically; prices are end-of-day closes. Not financial advice.