HCW Biologics Inc.HCWB

NasdaqHealthcarePharmaceutical Preparations
Price (close)
$1.99
Market cap
$3.7M
P/E
—
Revenue (TTM)
$6.7M
Net income
-$5.6M
Dividend yield
—
1-year total return
-91.9%
Net margin
-83.8%
Revenue growth
700.2%
Debt / equity
0.88x

What HCW Biologics Inc. does.

HCW Biologics Inc. (“HCW Biologics” or the “Company”) is a clinical-stage biopharmaceutical company developing transformative fusion immunotherapeutics to support or treat diseases promoted by chronic inflammation. We have created novel compounds that represent a new class of drugs that we believe have the potential to fundamentally change the treatment of autoimmune disorders and other proinflammatory diseases, cancer and senescence-associated dysplasia. Among other things, we have begun commercialization of certain commercial-ready proprietary compounds for use as reagents in the production of immunotherapeutics for the treatment of infectious diseases and cancer. We want our products to improve patients’ healthspan as well as their quality of life, and possibly extend longevity.

Chronic inflammation is believed to be a significant contributing factor to the cause for many diseases and conditions that diminish health span and quality of life. The induction and retention of low-grade inflammation in the human body is mainly the result of persistent activation of immune cells and the accumulation of non-proliferative but metabolically active senescent cells.

Senescence is a physiologic process important in promoting wound healing, tissue homeostasis, regeneration, embryogenesis, fibrosis regulation, and tumorigenesis suppression. However, accumulation of senescent cells with Senescence-Associated Phenotype (“SASP”) proinflammatory factors has been implicated as a major source of chronic sterile inflammation leading to many aging-related pathologies. SASP factors, including proinflammatory cytokines, chemokines, and proteinases, drive an inflammation cycle. Senescence is considered a stress response and can be induced by a wide range of intrinsic and extrinsic insults. Over time, these insults cause normal tissue cells to enter a senescent state of irreversible growth arrest accompanied by the release of SASP factors. The inflammation cycle promoted by SASP factors also activates immune cells. Similar to senescent cells, prolonged activation of immune cells promote the release of highly proinflammatory cytokines. Unresolved activation of immune cells leads to chronic low-grade inflammation, which perpetuates this cycle.

Revenue and profit, by fiscal year.

Fiscal year202020212022202320242025
Revenue$4.1M$0$6.7M$2.8M$2.6M$54,232
Net income-$5.8M-$12.9M-$14.9M-$25.0M-$30.0M-$8.0M
Free cash flow-$10.6M-$11.0M-$20.7M-$28.7M-$14.5M-$13.4M

More on HCWB.

Figures from HCW Biologics Inc.'s filings with the U.S. SEC, standardised automatically; prices are end-of-day closes. Not financial advice.